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KMID : 0363320080290030657
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Journal of Korean Oriental Internal Medicine
2008 Volume.29 No. 3 p.657 ~ p.665
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Effects of Acupuncture at ST36 on Blood Pressure and Endothelial Dependent Vasodilation in Hypertensive Patients
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Bae Hyung-Sup
Shin Ae-sook
Park Sung-Wook
Sohn Il-Suk
Jung Woo-Sang
Moon Sang-Kwan
Park Jung-Mi
Ko Chang-Nam
Cho Ki-Ho
Kim Young-Suk
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Abstract
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Objectives : The objective of this study was to assess the effect of acupuncture applied at the ST36 point on blood pressure and endothelial dependent vasodilation in hypertensive patients.
Methods : 24 hypertensive patients were recruited and randomized to a study group (12 subjects) or a control group (12 subjects). Both groups took FMD (endothelial-dependant, flow-mediated dilation) measurement and then acupuncture needles were inserted at ST36 for the study group. In the control group, they took sham acupuncture as a control. FMD was rechecked after 10-min acupuncture treatment. Blood pressure was measured before and after acupuncture treatment.
Results : FMD increased significantly in the study group after acupuncture (9.52.0% to 11.12.2%), but not in the control group. In both groups, there were no changes in blood pressure and heart rate.
Conclusions : Acupuncture on ST36 appears to improve endothelial dysfunction of hypertensive patients and this might result from inducing activation of endothelium-derived nitric oxide.
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KEYWORD
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Flow-mediated dilation (FMD), Endothelial dysfunction, Acupuncture, ST36, Hypertension
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